Stir together the mayo, sriracha, and lime juice and refrigerate until burgers are ready.
Add the beef, garlic, peppers, red onion, cilantro, lime juice, fish sauce, and salt and pepper to a medium bowl. With your hands, mix the beef mixture to evenly distribute the vegetables and seasonings. Form four beef patties.
Coat a cast iron skillet with cooking spray and bring to medium-high heat. Once the pan is hot, add the burgers. Cook on medium-high heat for 4-5 minutes on each side.
Serve with sriracha mayo on hamburger buns of choice and garnish with extra cilantro and a lime wedge.